Friday, May 29, 2009

Paxil As We Know It Today

Published in 1992 by the pharmaceutical company GlaxoSmithKline, Paxil is well known for its effectiveness in treating depression, obsessive compulsive disorder and other anxiety disorders or phobias.

In some countries of the Western Hemisphere, including the United States, Paxil (and Paxil CR) is the brand name for paroxetine. Paxil is considered one of the new antidepressants. These new drugs have fewer side effects than older antidepressants, and side effects that occur more people are in charge of taking these medicines. Paxil was approved by the Food and Drug Administration (FDA) for treating obsessive-compulsive disorder (OCD) and panic disorders. The doctors also legally prescribed Paxil for other diseases such as bulimia, premenstrual syndrome, alcohol and nicotine dependence.

Known as the selection of specific serotonin reuptake inhibitors (SSRIs), these drugs are currently the most frequently prescribed antidepressants. Often, a chemical imbalance as by non-specialists, medical studies note that depression can be caused by an imbalance of serotonin in the brain.

Nerve cells in the brain communicate with each other by passing messages through small spaces between cells - synapses. Cells send information to the release of neurotransmitters. One is known as the neurotransmitter serotonin. If freedom of serotonin is accepted by the recipient cell, there is communication between cells and messages are transmitted. However, some serotonin is lost in the process while others returned to the cell of origin. SSRIs inhibit the reuptake of serotonin, which has been published, which increases the level of serotonin available to facilitate communication from cell to cell.

Based on the assumption that depression is associated with a lack of stimulation of receptor neurons in a synapse, to stimulate the recipient cell, SSRIs inhibit the reuptake of serotonin. In prescribing an SSRI drugs like Paxil, the serotonin reuptake is inhibited, allowing the neurotransmitter to stay in the synaptic gap and longer than usual. This allows the cell receptor of serotonin and the opportunity to acknowledge once again with the hope that recognition occurs, and the recipient cell will be fully encouraged.

SSRIs affect only those responsible for the serotonin reuptake pump, compared to older antidepressants, which affect other neurotransmitters as well. Therefore, SSRIs are described as "selective" and the absence of certain adverse drug reactions before.

Before SSRIs were developed, most commonly prescribed antidepressants known as tricyclic antidepressants, sometimes referred to as the Act. The effectiveness of drugs against TCAs SSRIs appears to be negligible. However, SSRIs have a high toxic dose, which makes them less hazardous in case of a patient that is suicide. Some general side effects of SSRIs include nausea, headaches, anxiety, difficulty sleeping or restlenssness. Studies suggest that SSRIs such as Paxil in May to promote the growth of new neural pathways. In addition, SSRIs May protect against neurotoxicity caused by other compounds, as well as the depression itself.

Prescription Paxil in North America has been approved for patients 18 years or more.

On December 13, 2006, U.S. Food and Drug Administration, an advisory panel recommended that black box warnings on SSRIs be raised from 18 to 25 years of age. Although the FDA is not bound to follow the recommendations of its advisory committees, it usually does.